DiaPat® - the key to your health

The company

DiaPat GmbH was founded in Hanover in 2003. The company offers diagnostic tests for the early detection of diseases and is a leader in this field due to its innovative technology. The method is based on the analysis of proteins that play an outstanding role as information carriers in the human body. In addition to diagnostics, the DiaPat® procedure also enables therapy monitoring in the sense of personalized medicine.The main corporate goal is to enable the early detection of diseases, significantly improve the prospects of healing and thus contribute to an improved quality of life for people and the affected patients.

The technology

What is DiaPat®?

The DiaPat® technology is based on the knowledge that pathological changes in the human body can be indicated very early on at the protein level. These proteins are not only found in the corresponding cells of organs, but also in body fluids such as urine.

DiaPat® analyzes the relevant information carriers from the urine - thousands of proteins and their fragments (peptides) - and uses them to form diagnostic patterns (DiaPat).

The non-invasive DiaPat® test enables reliable early detection of diseases. In addition, the DiaPat® method allows the course of the disease to be monitored and targeted and individual treatment.

The DiaPat® technology has been clinically validated and published in over 350 articles in recognized scientific journals. The U.S. Food ans Drug Administration (FDA) has accepted the technology.

Detailed scientific information can be found at: mosaiques-diagnostics.com

The analytical procedure

The DiaPat® technology is based on the coupling of two established measuring methods: capillary electrophoresis and mass spectrometry. The proteins are first separated in the electrical voltage field (25,000 volts) and then measured in the mass spectrometer. The data obtained are evaluated using specially developed software and compared with the DiaPat® database. In the next step, disease-specific proteins (biomarkers) are identified from the data using complex statistical procedures. The biomarkers found are combined in an algorithm ("artificial intelligence") and thus achieve an accuracy that was previously not thought possible.

The analysis of your urine sample with the DiaPat® test enables a holistic picture of your state of health. Diseases can thus be detected as early as possible and treated individually with a targeted therapy. At this point, the disease can still be stopped before the first symptoms are visible or the disease breaks out.

Why urine and not blood?

The information carriers in blood are broken down by enzymes (proteases) shortly after collection. So the amount of information contained in the blood depends strongly on how quickly it was processed. However, this process is difficult to control. Urine, on the other hand, is very stable as an information carrier. When the urine leaves the bladder, the degradation processes of the enzymes have already been completed. Therefore, your urine sample can also be transported uncooled in the urine tube (monovette). Bacterial contamination is additionally prevented by the stabiliser in the urine tube.

Prof. Dr. Dr. Harald Mischak

Lower Saxony Innovation Award 2018

The team 2018